CHIR-98014 - CD BioSciences

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CHIR-98014

CHIR-98014

SPC-00543

CHIR-98014

CAS No. 252935-94-7

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10 mM (1 mL in DMSO) Online Inquiry
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100 mg Online Inquiry
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GSK-3 inhibitor

Description
CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Product Details
CAS No. CAS No. 252935-94-7
Description CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Formula C20H17Cl2N9O2
Molecular Weight 486.31
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms CT98014
SMILES C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.