Online Inquiry
CHIR-124
SPC-00542
CAS No. 405168-58-3
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 2 mg | Online Inquiry |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Chk inhibitor
| Description |
|---|
| CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 405168-58-3 |
| Description | CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2. |
| Formula | C23H22ClN5O |
| Molecular Weight | 419.91 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | C1CN2CCC1C(C2)NC3=C(C(=O)NC4=C3C=C(C=C4)Cl)C5=NC6=CC=CC=C6N5 |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.