Cerdulatinib (PRT062070) - CD BioSciences

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Cerdulatinib (PRT062070)

Cerdulatinib (PRT062070)

SPC-00527

Cerdulatinib (PRT062070)

CAS No. 1369761-01-2

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JAK inhibitor ; Syk inhibitor

Description
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
Product Details
CAS No. CAS No. 1369761-01-2
Description Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
Formula C20H28ClN7O3S
Molecular Weight 482
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms PRT2070
SMILES CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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