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CEP290 Antibody
SPA-02154
| Size | Price |
| 100 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CEP290 |
| Gene Abbr. | CEP290 |
| Gene ID | 80184 |
| Full Name | centrosomal protein 290 |
| Alias | 3H11Ag, BBS14, CT87, JBTS5, LCA10 |
| Introduction | This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Peptide with sequence C-RNSKHLKQQQYRAEN corresponding to internal region according to NP_079390.3. |
| Usage | |
|---|---|
| Application | IF, IHC, ELISA |
| Dilutions | Immunofluorescence (2-3 µg/mL); ELISA (1:128000) |
| Reactivity | Human |
| Specificity | Despite similarity of the immunizing peptide with the mouse protein, this antibody was demonstrated to weak for mouse Cep290. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.