Online Inquiry
Celastrol
SPC-00521
CAS No. 34157-83-0
| Size | Price |
| 10 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Proteasome inhibitor ; Autophagy activator ; Apoptosis related activator ; Mitophagy activator
| Description |
|---|
| Celastrol (Tripterine) is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 34157-83-0 |
| Description | Celastrol (Tripterine) is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy. |
| Formula | C29H38O4 |
| Molecular Weight | 450.61 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Tripterine |
| SMILES | CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.