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Cdc14A Antibody
SPA-02089
Size | Price |
0.1 mL | Online Inquiry |
25 µL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Cdc14A |
Gene Abbr. | CDC14A |
Gene ID | 8556 |
Full Name | cell division cycle 14A |
Alias | DFNB105, DFNB32, DFNB35, cdc14, hCDC14 |
Introduction | The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | 1F11 |
Isotype | IgG2A Kappa |
Immunogen | CDC14A (NP_003663, 431 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPE. |
Usage | |
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Application | WB, ELISA, IF |
Reactivity | Human |
Specificity | CDC14A - CDC14 cell division cycle 14 homolog A (S. cerevisiae). |
Storage & Handling | |
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Storage Buffer | In 1X PBS, pH 7.4. |
Preservative | No Preservative |
Storage Temp. | Aliquot and store at -20 °C or -80 °C. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.