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CD74 (-) Cell Line
SPL-00870
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| CD74 (-) |
| Target Information | |
|---|---|
| Target Name | CD74 |
| Gene Abbr. | CD74 |
| Gene ID | 972 |
| Full Name | CD74 molecule |
| Alias | DHLAG, HLADG, II, Ia-GAMMA, p33 |
| Species | Human |
| Introduction | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | CD74 (-) |
| Description | CD74 (-) |
| Parental Cell Line | C631 |
| Handling Specifications | |
|---|---|
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.