CD27/TNFRSF7 Antibody - CD BioSciences

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CD27/TNFRSF7 Antibody

CD27/TNFRSF7 Antibody

SPA-01883

Size Price
100 µL Online Inquiry
More Options Online Inquiry
Target Information
Target Name CD27
Gene Abbr. CD27
Gene ID 939
Full Name CD27 molecule
Alias S152, S152. LPFS2, T14, TNFRSF7, Tp55
Introduction The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq]
Product Details
Host Mouse
Clonality Monoclonal
Clone No. LPFS2/1611
Isotype IgG1
Immunogen Recombinant human CD22 protein (exact sequence is proprietary).
Usage
Application FC, IF, IHC
Dilutions Flow Cytometry (0.5-1 µg/10^6 cells); Immunofluorescence (0.5-1 µg/mL)
Reactivity Human
Storage & Handling
Storage Buffer 10 mM PBS with 0.05% BSA.
Preservative 0.05% Sodium Azide
Storage Temp. Store at 4 °C.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.