Online Inquiry
CD25/IL-2R alpha Antibody
SPA-05738
| Size | Price |
| 0.5 mL | Online Inquiry |
| 0.1 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-2 Receptor |
| Gene Abbr. | IL2RA |
| Gene ID | 3559 |
| Full Name | interleukin 2 receptor subunit alpha |
| Alias | CD25, IDDM10, IL2R, IMD41, TCGFR |
| Introduction | The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | PC61.5.3 |
| Isotype | IgG1 |
| Immunogen | B6.1 CTL cell line. |
| Usage | |
|---|---|
| Application | FC, IHC, IP |
| Dilutions | Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500) |
| Reactivity | Mouse |
| Specificity | This reacts with the low affinity alpha chain of the IL2 receptor present on activated T and B cells in mice. Clone PC61.5.3 is reported to inhibit IL2 binding and IL2 dependent proliferation. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.