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CD25/IL-2R alpha Antibody
SPA-05737
| Size | Price |
| 0.5 mL | Online Inquiry |
| 0.1 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-2 Receptor |
| Gene Abbr. | IL2RA |
| Gene ID | 3559 |
| Full Name | interleukin 2 receptor subunit alpha |
| Alias | CD25, IDDM10, IL2R, IMD41, TCGFR |
| Introduction | The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | IL2R.1 |
| Isotype | IgG1 Kappa |
| Immunogen | BALB/C mice were injected with recombinant human interleukin-2 receptor. |
| Usage | |
|---|---|
| Application | IF, IHC |
| Dilutions | Immunofluorescence (1:10-1:500); Immunohistochemistry (1:10-1:500) |
| Reactivity | Human, Mouse |
| Specificity | This antibody is specific to a 55 kDa protein known as interleukin 2-receptor (IL-2R alpha). IL-2R alpha is over expressed on the surface of activated T cells, HTLV-1 or HTLV-2 positive T cell lines. It is moderately expressed on activated B cells, NK-cells, and macrophages. |
| Storage & Handling | |
|---|---|
| Storage Buffer | EDTA, pH 8.0, containing less than 0.1% sodium azide. |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C. |
| Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.