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CD14 Antibody
SPA-01830
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CD14 |
| Gene Abbr. | CD14 |
| Gene ID | 929 |
| Full Name | CD14 molecule |
| Introduction | CD14 is a leucine-rich repeat-containing pattern recognition receptor with expression largely restricted to the monocyte/macrophage cell lineage. Research studies have shown that CD14 is a bacterial lipopolysaccharide (LPS) binding glycoprotein, expressed as either a GPI-linked membrane protein or a soluble plasma protein. LPS induces an upregulation of GPI-linked CD14 expression, which facilitates TLR4 signaling and macrophage activation in response to bacterial infection. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | M5E2 |
| Isotype | IgG2A Kappa |
| Immunogen | Human peripheral blood cells. |
| Usage | |
|---|---|
| Application | FC, IF, IHC |
| Dilutions | Flow Cytometry (< 2.0 μg/10^6 cells in 100 µL); Immunofluorescence (1:10-1:500); Immunohistochemistry (1:10-1:500) |
| MW(KDa) | 50-60 |
| Reactivity | Human, Porcine, Bovine, Canine, Primate |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.