Online Inquiry
CCR5 Antibody
SPA-01759
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CCR5 |
| Gene Abbr. | CCR5 |
| Gene ID | 1234 |
| Full Name | C-C motif chemokine receptor 5 (gene/pseudogene) |
| Alias | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5 |
| Introduction | CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha, MIP-1 beta, MCP-2, and RANTES. It also functions as a coreceptor for Macrophage Tropic HIV-1 infection. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 45502 |
| Isotype | IgG2B |
| Immunogen | NS0 mouse myeloma cell line transfected with human CCR5. Met1-Leu352. Accession # P51681. |
| Usage | |
|---|---|
| Application | FC |
| Dilutions | Flow Cytometry (2.5 μg/10^6 cells) |
| Reactivity | Human |
| Specificity | Specifically stains human CCR5 transfectants but not the parental cell line as detected by flow cytometry. It has also been shown to react with a CCR5/CCR2 chimera (5222) containing the amino-terminal domain of CCR5. However, this antibody does not react with CCR5 present on unfixed stimulated human PBMCs by flow cytometry. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.