CCR4 Antibody - CD BioSciences

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CCR4 Antibody

CCR4 Antibody

SPA-01757

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100 µg Online Inquiry
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Target Information
Target Name CCR4
Gene Abbr. CCR4
Gene ID 1233
Full Name C-C motif chemokine receptor 4
Alias CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13
Introduction CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 205410
Isotype IgG2B
Immunogen Human CCR4 transfectants. Met1-Leu360. P51679.
Usage
Application FC
Dilutions Flow Cytometry (0.25 μg/10^6 cells)
Reactivity Human
Specificity Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.