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CCR4 Antibody
SPA-01755
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CCR4 |
| Gene Abbr. | CCR4 |
| Gene ID | 1233 |
| Full Name | C-C motif chemokine receptor 4 |
| Alias | CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13 |
| Introduction | CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic peptide DTTQDETVYNSYYFYESMP-C corresponds to amino acid residues 8 - 26 of mouse CCR4 with cysteine added for coupling to a carrier protein. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC, IHC |
| Dilutions | Western Blot (1:500); ELISA (1:25000); Flow Cytometry (2 µL/10-6 cells); Immunohistochemistry (1:250) |
| Reactivity | Mouse |
| Specificity | Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region. The antibody recognizes mouse CCR4 and has no cross-reactivity to human CCR4. |
| Storage & Handling | |
|---|---|
| Storage Buffer | 10 mM KHPO4, 0.14 M NaCl and 1.0 mg/mL BSA. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Aliquot and store at -20 °C or -80 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.