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CCL2/JE/MCP-1 Antibody
SPA-01583
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CCL2/MCP1 |
| Gene Abbr. | CCL2 |
| Gene ID | 6347 |
| Full Name | C-C motif chemokine ligand 2 |
| Alias | GDCF-2, HC11, HSMCR30, MCAF, MCP-1 |
| Introduction | CCL2, also known as JE or MCP-1 (monocyte chemoattractant protein-1), is a CC chemokine produced by fibroblasts, macrophages, astrocytes, mast cells, endothelial cells and osteoblasts. It functions as a chemoattractant through ligations with CCR2 on monocytes, macrophages and lymphocytes. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | MNA1 |
| Isotype | IgG1 |
| Immunogen | The antibody reacts with both human natural and recombinant MCP1 in ELISA. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC, IF, IHC, IP |
| Dilutions | Western Blot (1:100-1:2000); ELISA (1:100-1:2000); Flow Cytometry (1:10-1:1000); Immunofluorescence (1:10-1:500); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500) |
| Reactivity | Human |
| Specificity | The antibody reacts with both human natural and recombinant MCP1 in ELISA. MCP1 is a member of the CC subfamily of chemokines. MCP1 is a proinflammatory cytokine which acts both as an activation factor and as chemokine for monocytic cells. The antibody inhibits the biological activity of natural and recombinant human MCP1. The antigen specificity was assessed by ELISA. The antigen specificity was further assessed by immunoprecipitation and Western Blot. No crossreactivities with other cytokines have been detected. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS containing 0.1% BSA. |
| Preservative | No Preservative |
| Storage Temp. | Store at 4 °C. |
| Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.