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CCL23/Ck beta 8-1/MIP3 Antibody
SPA-01625
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CCL23/MIP3 |
| Gene Abbr. | CCL23 |
| Gene ID | 6368 |
| Full Name | C-C motif chemokine ligand 23 |
| Alias | CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3 |
| Introduction | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | E. coli-derived recombinant human CCL23/Ck beta 8‑1. Met46-Asn137. AAD10846. |
| Usage | |
|---|---|
| Application | WB |
| Dilutions | Western Blot (0.1 µg/mL); Neutralization (0.15-0.75 µg/mL) |
| Reactivity | Human |
| Specificity | Detects CCL23/Ck beta 8‑1 in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, approximately 20% cross-reactivity with recombinant human MPIF-1 is observed. Neutralizes the biological activity of human CCL23/Ck beta 8‑1. It will also neutralize the biological activity of recombinant human MPIF-1 at a 10-fold higher Ig concentration. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.