CCL18/PARC Antibody - CD BioSciences

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CCL18/PARC Antibody

CCL18/PARC Antibody

SPA-01555

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Target Information
Target Name CCL18/PARC
Gene Abbr. CCL18
Gene ID 6362
Full Name C-C motif chemokine ligand 18
Alias AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1
Introduction This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq]
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen E. coli-derived recombinant human CCL18/PARC. Ala21-Ala89. P55774.
Usage
Application WB, FC
Dilutions Western Blot (0.1 µg/mL); Flow Cytometry (2.5 µg/10^6 cells)
Reactivity Human
Specificity Detects human CCL18/PARC in direct ELISAs and Western Blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) MIP-1 alpha and recombinant mouse MIP-1 alpha is observed and less than 10% cross-reactivity with rhMPIF‑1, recombinant viral (rv) MIP‑I, rvMIP‑II, rhHCC-1, and rhMIP-1δ is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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