CCL11/Eotaxin Antibody - CD BioSciences

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CCL11/Eotaxin Antibody

CCL11/Eotaxin Antibody

SPA-01509

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Target Information
Target Name CCL11/Eotaxin
Gene Abbr. CCL11
Gene ID 6356
Full Name C-C motif chemokine ligand 11
Alias SCYA11
Introduction This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq]
Product Details
Host Rat
Clonality Monoclonal
Clone No. 42285
Isotype IgG2A
Immunogen E. coli-derived recombinant mouse CCL11/Eotaxin. His24-Pro97. P48298.
Usage
Application WB, IHC
Dilutions Western Blot (1 µg/mL); Immunohistochemistry (8-25 µg/mL); Neutralization (3-30 µg/mL)
Reactivity Mouse
Specificity Detects mouse CCL11/Eotaxin in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, less than 10% cross-reactivity with recombinant human (rh) CCL11/Eotaxin, recombinant mouse CCL7, and rhCCL21 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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