Cav1.4 Antibody - CD BioSciences

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Cav1.4 Antibody

Cav1.4 Antibody

SPA-01478

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0.05 mL Online Inquiry
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Target Information
Target Name Cav1.4
Gene Abbr. CACNA1F
Gene ID 778
Full Name calcium voltage-gated channel subunit alpha1 F
Alias AIED, COD3, COD4, CORDX, CORDX3
Introduction This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants of the gene described here have been observed but have not been thoroughly characterized. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq]
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 3B2
Isotype IgG3 Kappa
Immunogen CACNA1F (NP_005174, 1878 a.a. ~ 1977 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQGTSSLYSDEESILSRFDEEDLGDEMACVHAL.
Usage
Application WB, ELISA
Dilutions Western Blot (1:500)
Reactivity Human
Specificity calcium channel, voltage-dependent, alpha 1F subunit.
Storage & Handling
Storage Buffer In 1X PBS, pH 7.4.
Preservative No Preservative
Storage Temp. Aliquot and store at -20 °C or -80 °C.
Handling Avoid freeze-thaw cycles.

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