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CARD9 Antibody
SPA-01357
Size | Price |
0.1 mL | Online Inquiry |
25 µL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | CARD9 |
Gene Abbr. | CARD9 |
Gene ID | 64170 |
Full Name | caspase recruitment domain family member 9 |
Alias | CANDF2, hCARD9 |
Introduction | Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kappaB. CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling. |
Product Details | |
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Host | Rabbit |
Clonality | Polyclonal |
Clone No. | N/A |
Isotype | IgG |
Immunogen | A 16 amino acid peptide near the carboxy terminus of human CARD9. The immunogen is located within the last 50 amino acids of CARD9. Amino Acid Squence: DRENTTGSDNTDDTEGS. |
Usage | |
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Application | WB, ELISA, IF |
Dilutions | Western Blot (2.5 µg/mL); ELISA (1:100-1:2000); Immunofluorescence (10 µg/mL) |
Reactivity | Human |
Storage & Handling | |
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Storage Buffer | PBS. |
Preservative | 0.02% Sodium Azide |
Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.