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Capivasertib (AZD5363)
SPC-00484
CAS No. 1143532-39-1
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Akt inhibitor
Description |
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AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2. |
Product Details | |
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CAS No. | CAS No. 1143532-39-1 |
Description | AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2. |
Formula | C21H25ClN6O2 |
Molecular Weight | 428.92 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | C1CN(CCC1(C(=O)NC(CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.