Capivasertib (AZD5363) - CD BioSciences

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Capivasertib (AZD5363)

Capivasertib (AZD5363)

SPC-00484

Capivasertib (AZD5363)

CAS No. 1143532-39-1

Size Price
10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
25 mg Online Inquiry
Bulk Size Online Inquiry

Akt inhibitor

Description
AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2.
Product Details
CAS No. CAS No. 1143532-39-1
Description AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2.
Formula C21H25ClN6O2
Molecular Weight 428.92
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CN(CCC1(C(=O)NC(CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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