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Canertinib (CI-1033)
SPC-00482
CAS No. 267243-28-7
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10 mg | Online Inquiry |
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100 mg | Online Inquiry |
200 mg | Online Inquiry |
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EGFR inhibitor ; HER2 inhibitor
Description |
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Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3. |
Product Details | |
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CAS No. | CAS No. 267243-28-7 |
Description | Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3. |
Formula | C24H25ClFN5O3 |
Molecular Weight | 485.94 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | PD183805 |
SMILES | C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4 |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.