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Camptothecin
SPC-00479
CAS No. 7689-03-4
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 100 mg | Online Inquiry |
| 250 mg | Online Inquiry |
| 500 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
ADC Cytotoxin inhibitor ; Topoisomerase inhibitor ; Apoptosis related activator
| Description |
|---|
| Camptothecin (NSC-100880, CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 7689-03-4 |
| Description | Camptothecin (NSC-100880, CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2. |
| Formula | C20H16N2O4 |
| Molecular Weight | 348.35 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC-100880, CPT |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.