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Calmodulin Antibody
SPA-01305
Size | Price |
25 µg | Online Inquiry |
100 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Calmodulin |
Gene Abbr. | CALM1 |
Gene ID | 801 |
Full Name | calmodulin 1 |
Alias | CALML2, CAM2, CAM3, CAMB, CAMC |
Introduction | Calmodulin is a ubiquitously expressed small protein mediating many cellular effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellular movement. Upon binding of four Ca2+ ions, calmodulin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase. Since calmodulin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodulin and its target proteins. |
Product Details | |
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Host | Rabbit |
Clonality | Polyclonal |
Clone No. | N/A |
Immunogen | Synthetic peptide surrounding Glu140 of human calmodulin. |
Source/Purification | Antibodies are produced by immunizing animals with a synthetic peptide surrounding Glu140 of human calmodulin. Antibodies are purified by peptide affinity chromatography. |
Usage | |
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Application | WB |
Dilutions | Western Blot (1:1000) |
MW(KDa) | 17 |
Reactivity | Mouse, Rat |
Sensitivity | Endogenous |
Specificity | It detects endogenous levels of total calmodulin protein. |
Storage & Handling | |
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Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol. |
Preservative | No Preservative |
Storage Temp. | Store at -20 °C. |
Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.