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C3 (-) Cell Line
SPL-00740
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| C3 (-) |
| Target Information | |
|---|---|
| Target Name | Complement C3 |
| Gene Abbr. | C3 |
| Gene ID | 718 |
| Full Name | complement C3 |
| Alias | AHUS5, ARMD9, ASP, C3a, C3b |
| Species | Human |
| Introduction | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | C3 (-) |
| Description | C3 (-) |
| Parental Cell Line | C631 |
| Handling Specifications | |
|---|---|
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.