C3 cDNA ORF Clone, Cynomolgus, untagged - CD BioSciences

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C3 cDNA ORF Clone, Cynomolgus, untagged

C3 cDNA ORF Clone, Cynomolgus, untagged

SPD-03635

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Description
Full length Clone DNA of Cynomolgus complement C3
Target Information
Species Cynomolgus
Target Name Complement C3
Gene Abbr. C3
Gene ID 102131458
Full Name complement C3
Introduction The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
Product Details
Description Full length Clone DNA of Cynomolgus complement C3
NCBI Ref Seq XM_005587719.2
RefSeq ORF Size 4992 bp
Sequence Information Identical with the Gene Bank Ref. ID sequence.
Vector pCMV3-untagged
Promoter Enhanced CMV mammalian cell promoter
Restriction Sites HindIII + XbaI (6.1kb + 4.99kb)
Quality Control The plasmid is confirmed by full-length sequencing.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.
Usage
Sequencing Primers T7 (TAATACGACTCACTATAGGG); BGH (TAGAAGGCACAGTCGAGG);
Antibiotic in E.coli Ampicillin
Antibiotic in Mammalian cell Hygromycin
Application Stable or Transient mammalian expression
Shipping Each tube contains lyophilized plasmid.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.

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