Brivanib (BMS-540215) - CD BioSciences

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Brivanib (BMS-540215)

Brivanib (BMS-540215)

SPC-00451

Brivanib (BMS-540215)

CAS No. 649735-46-6

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10 mM (1 mL in DMSO) Online Inquiry
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VEGFR inhibitor ; FGFR inhibitor

Description
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
Product Details
CAS No. CAS No. 649735-46-6
Description Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
Formula C19H19FN4O3
Molecular Weight 370.38
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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