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Bortezomib (PS-341)
SPC-00432
CAS No. 179324-69-7
| Size | Price |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| 300 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Proteasome inhibitor ; Autophagy inhibitor ; ERK activator ; NF-κB inhibitor
| Description |
|---|
| Bortezomib (PS-341, LDP-341, MLM341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 179324-69-7 |
| Description | Bortezomib (PS-341, LDP-341, MLM341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors. |
| Formula | C19H25BN4O4 |
| Molecular Weight | 384.24 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | LDP-341, MLM341 |
| SMILES | B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.