BMP-5 Antibody - CD BioSciences

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BMP-5 Antibody

BMP-5 Antibody

SPA-01096

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Target Information
Target Name BMP-5
Gene Abbr. BMP5
Gene ID 653
Full Name bone morphogenetic protein 5
Introduction This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant human BMP‑5.
Usage
Application WB, IHC
Dilutions Western Blot (0.1 µg/mL); Immunohistochemistry (5-15 µg/mL); Neutralization (6-24 µg/mL)
Reactivity Human
Specificity Detects human BMP‑5 in direct ELISAs and Western Blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) BMP‑2, rhBMP-4, rhBMP-6, rhBMP-7, and rhBMP-8 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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