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Bisindolylmaleimide I (GF109203X)
SPC-00404
CAS No. 133052-90-1
| Size | Price |
| 1 mg | Online Inquiry |
| 10 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PKC inhibitor
| Description |
|---|
| Bisindolylmaleimide I (GF109203X) is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 133052-90-1 |
| Description | Bisindolylmaleimide I (GF109203X) is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor. |
| Formula | C25H24N4O2 |
| Molecular Weight | 412.48 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | GO 6850 , Bisindolylmaleimide I |
| SMILES | CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.