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Binimetinib (MEK162)
SPC-00398
CAS No. 606143-89-9
| Size | Price |
| 10 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
MEK inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 606143-89-9 |
| Description | Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3. |
| Formula | C17H15BrF2N4O3 |
| Molecular Weight | 441.23 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | ARRY-162,ARRY-438162 |
| SMILES | CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.