Online Inquiry
Beta-endorphin Antibody
SPA-03409
Size | Price |
0.05 mL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
---|---|
Target Name | Endorphin |
Gene Abbr. | POMC |
Gene ID | 5443 |
Full Name | proopiomelanocortin |
Alias | ACTH, CLIP, LPH, MSH, NPP |
Introduction | Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). beta-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the u-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects |
Product Details | |
---|---|
Host | Mouse |
Clonality | Monoclonal |
Clone No. | B31.15 |
Isotype | IgG1 |
Immunogen | Human beta Endorphin (full length native protein). |
Usage | |
---|---|
Application | IHC |
Dilutions | Immunohistochemistry (10-20 µg/mL) |
Reactivity | Human |
Specificity | The antibody B31.15 reacts with human beta Endorphin, an endogenous opiate derived from ACTH gene. ACTH (Corticotropin; human 39 aa) is synthesized by the anterior pituitary gland and stimulates the adrenal cortex; 6 hormones are derived from one ACTH gene: ACTH, lipotropin, alpha-MSH, beta-MSH, endorphin, and one other. |
Storage & Handling | |
---|---|
Storage Buffer | PBS (pH 7.4). |
Preservative | 15 mM Sodium Azide |
Storage Temp. | Store at 4 °C. |
Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.