Beta-endorphin Antibody - CD BioSciences

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Beta-endorphin Antibody

Beta-endorphin Antibody

SPA-03409

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0.05 mL Online Inquiry
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Target Information
Target Name Endorphin
Gene Abbr. POMC
Gene ID 5443
Full Name proopiomelanocortin
Alias ACTH, CLIP, LPH, MSH, NPP
Introduction Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). beta-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the u-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects
Product Details
Host Mouse
Clonality Monoclonal
Clone No. B31.15
Isotype IgG1
Immunogen Human beta Endorphin (full length native protein).
Usage
Application IHC
Dilutions Immunohistochemistry (10-20 µg/mL)
Reactivity Human
Specificity The antibody B31.15 reacts with human beta Endorphin, an endogenous opiate derived from ACTH gene. ACTH (Corticotropin; human 39 aa) is synthesized by the anterior pituitary gland and stimulates the adrenal cortex; 6 hormones are derived from one ACTH gene: ACTH, lipotropin, alpha-MSH, beta-MSH, endorphin, and one other.
Storage & Handling
Storage Buffer PBS (pH 7.4).
Preservative 15 mM Sodium Azide
Storage Temp. Store at 4 °C.
Handling Do not freeze.

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