Berbamine - CD BioSciences

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Berbamine

Berbamine

SPC-00364

Berbamine

CAS No. 478-61-5

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Bcr-Abl inhibitor ; NF-κB inhibitor ; Apoptosis related activator ; CaMK modulator

Description
Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
Product Details
CAS No. CAS No. 478-61-5
Description Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
Formula C37H40N2O6
Molecular Weight 608.72
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms BA, BBM
SMILES CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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