Online Inquiry
Berbamine
SPC-00364
CAS No. 478-61-5
Size | Price |
5 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Bcr-Abl inhibitor ; NF-κB inhibitor ; Apoptosis related activator ; CaMK modulator
Description |
---|
Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII). |
Product Details | |
---|---|
CAS No. | CAS No. 478-61-5 |
Description | Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII). |
Formula | C37H40N2O6 |
Molecular Weight | 608.72 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | BA, BBM |
SMILES | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC |
Usage | |
---|---|
Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.