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Bcl-xL Antibody
SPA-00991
| Size | Price |
| 100 µg | Online Inquiry |
| 25 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Bcl-xL |
| Gene Abbr. | BCL2L1 |
| Gene ID | 598 |
| Full Name | BCL2 like 1 |
| Alias | BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52 |
| Introduction | Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits its apoptotic effect and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions. Bcl-xL is phosphorylated by JNK following treatment with microtubule-damaging agents such as paclitaxel, vinblastine and nocodazole. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to amino acids 61-79 (DSPAVNGATAHSSSLDARE) of human Bcl-XL was used as immunogen; GenBank no. CAA80661.1. The immunogen sequence is 94% conserved in Bcl-XS. |
| Usage | |
|---|---|
| Application | WB, IHC, IP |
| Dilutions | Western Blot (1:1000-1:2000); Immunohistochemistry (1:1000-1:5000); Immunoprecipitation (1:50-1:200) |
| MW(KDa) | 30 |
| Reactivity | Human, Mouse, Rat, Canine, Mammal |
| Specificity | Bcl-XL+S. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Whole antisera. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.