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Bcl-xL Antibody
SPA-00987
| Size | Price |
| 100 µg | Online Inquiry |
| 25 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Bcl-xL |
| Gene Abbr. | BCL2L1 |
| Gene ID | 598 |
| Full Name | BCL2 like 1 |
| Alias | BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52 |
| Introduction | Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits its apoptotic effect and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions. Bcl-xL is phosphorylated by JNK following treatment with microtubule-damaging agents such as paclitaxel, vinblastine and nocodazole. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | OTI4A9 |
| Isotype | IgG2A |
| Immunogen | Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL. |
| Usage | |
|---|---|
| Application | WB, IF, IHC |
| Dilutions | Western Blot (1:500); Immunofluorescence (1:100) |
| MW(KDa) | 30 |
| Reactivity | Human, Mouse |
| Specificity | This antibody is specific for Homo sapiens BCL2-like 1 (BCL2L1), nuclear gene encoding mitochondrial protein, transcript variant 1. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS (pH 7.3), 1.0% BSA and 50% Glycerol. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.