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BAY 11-7082
SPC-00334
CAS No. 19542-67-7
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
IκB/IKK inhibitor ; Apoptosis related activator ; DUB inhibitor
| Description |
|---|
| BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 19542-67-7 |
| Description | BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells. |
| Formula | C10H9NO2S |
| Molecular Weight | 207.25 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | BAY 11-7821 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)C=CC#N |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.