Online Inquiry
Baricitinib phosphate
SPC-00330
CAS No. 1187595-84-1
Size | Price |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
JAK inhibitor ; COVID-19 inhibitor
Description |
---|
Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19. |
Product Details | |
---|---|
CAS No. | CAS No. 1187595-84-1 |
Description | Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19. |
Formula | C16H20N7O6PS |
Molecular Weight | 469.41 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | INCB-028050 phosphate, LY-3009104 phosphate |
SMILES | CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O |
Usage | |
---|---|
Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.