Baricitinib phosphate - CD BioSciences

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Baricitinib phosphate

Baricitinib phosphate

SPC-00330

Baricitinib phosphate

CAS No. 1187595-84-1

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JAK inhibitor ; COVID-19 inhibitor

Description
Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.
Product Details
CAS No. CAS No. 1187595-84-1
Description Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.
Formula C16H20N7O6PS
Molecular Weight 469.41
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms INCB-028050 phosphate, LY-3009104 phosphate
SMILES CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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