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Bag-1 Antibody
SPA-00863
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Bag-1 |
| Gene Abbr. | BAG1 |
| Gene ID | 573 |
| Full Name | BAG cochaperone 1 |
| Alias | BAG-1, HAP, RAP46 |
| Introduction | Bag-1 (Bcl-2-associated Athanogene 1) is a 31-kDa protein with an apparent molecular mass of 46 kDa that can bind to Bcl-2 and enhance its anti-apoptotic effect, resulting in increased protection from cell death induced by apoptotic stimuli. Bag-1 shares no significant homology with Bcl-2 or other Bcl-2 family proteins. The C-terminal region of Bag-1 binds the PDGF and HGF Receptor, and enhances growth factor-mediated protection from apoptosis. This represents a link between growth factor receptors and anti-apoptotic mechanisms. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | GP3.10G3E2 |
| Isotype | IgG1 |
| Immunogen | E. coli-derived recombinant human Bag-1. |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (0.5 µg/mL); Immunoprecipitation (0.6 µg/10^6 cells) |
| Reactivity | Human |
| Validation | Knockout Validated. |
| Specificity | Detects the 36 kDa and 50 kDa isoforms of human Bag-1. Does not detect mouse Bag-1. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.