AZD1390 - CD BioSciences

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AZD1390

AZD1390

SPC-00291

AZD1390

CAS No. 2089288-03-7

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ATM/ATR inhibitor

Description
AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.
Product Details
CAS No. CAS No. 2089288-03-7
Description AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.
Formula C27H32FN5O2
Molecular Weight 477.57
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)N1C2=C(C=NC3=CC(=C(C=C32)C4=CN=C(C=C4)OCCCN5CCCCC5)F)N(C1=O)C
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.