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Axitinib
SPC-00273
CAS No. 319460-85-0
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
50 mg | Online Inquiry |
100 mg | Online Inquiry |
200 mg | Online Inquiry |
Bulk Size | Online Inquiry |
VEGFR inhibitor ; c-Kit inhibitor ; PDGFR inhibitor
Description |
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Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively. |
Product Details | |
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CAS No. | CAS No. 319460-85-0 |
Description | Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively. |
Formula | C22H18N4OS |
Molecular Weight | 386.47 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | AG 013736 |
SMILES | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4 |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.