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Aurora A Inhibitor I (TC-S 7010)
SPC-00262
CAS No. 1158838-45-9
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
50 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Aurora Kinase inhibitor ; Apoptosis related activator
Description |
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Aurora A Inhibitor I (TC-S 7010) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway. |
Product Details | |
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CAS No. | CAS No. 1158838-45-9 |
Description | Aurora A Inhibitor I (TC-S 7010) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway. |
Formula | C31H31ClFN7O2 |
Molecular Weight | 588.07 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.