AT7519 - CD BioSciences

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AT7519

AT7519

SPC-00247

AT7519

CAS No. 844442-38-2

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10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
10 mg Online Inquiry
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CDK inhibitor ; GSK-3 inhibitor ; Apoptosis related activator

Description
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also inhibits GSK3β with IC50 of 89 nM. AT7519 induces apoptosis. Phase 2.
Product Details
CAS No. CAS No. 844442-38-2
Description AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also inhibits GSK3β with IC50 of 89 nM. AT7519 induces apoptosis. Phase 2.
Formula C16H17Cl2N5O2
Molecular Weight 382.24
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.