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ARNT (-) Cell Line
SPL-00467
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| ARNT (-) |
| Target Information | |
|---|---|
| Target Name | HIF-1β |
| Gene Abbr. | ARNT |
| Gene ID | 405 |
| Full Name | aryl hydrocarbon receptor nuclear translocator |
| Alias | HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA |
| Species | Human |
| Introduction | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | ARNT (-) |
| Description | ARNT (-) |
| Parental Cell Line | C631 |
| Handling Specifications | |
|---|---|
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.