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APPL1 (-) Cell Line
SPL-00281
Size | Price |
1 Unit | Online Inquiry |
Description |
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APPL1 (-) |
Target Information | |
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Target Name | APPL |
Gene Abbr. | APPL1 |
Gene ID | 26060 |
Full Name | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
Alias | APPL, DIP13alpha, MODY14 |
Species | Human |
Introduction | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]. |
Product Details | |
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Cell Line Model | HAP1 |
Genotype | APPL1 (-) |
Description | APPL1 (-) |
Parental Cell Line | C631 |
Handling Specifications | |
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Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.