APPL1 (-) Cell Line - CD BioSciences

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APPL1 (-) Cell Line

APPL1 (-) Cell Line

SPL-00281

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Description
APPL1 (-)
Target Information
Target Name APPL
Gene Abbr. APPL1
Gene ID 26060
Full Name adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Alias APPL, DIP13alpha, MODY14
Species Human
Introduction The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008].
Product Details
Cell Line Model HAP1
Genotype APPL1 (-)
Description APPL1 (-)
Parental Cell Line C631
Handling Specifications
Disclaimer This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.