Apatinib - CD BioSciences

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Apatinib

Apatinib

SPC-00207

Apatinib

CAS No. 811803-05-1

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VEGFR inhibitor ; c-RET inhibitor ; c-Kit inhibitor ; Src inhibitor ; Autophagy activator ; Apoptosis related activator

Description
Apatinib is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret, c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.
Product Details
CAS No. CAS No. 811803-05-1
Description Apatinib is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret, c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.
Formula C24H23N5O
Molecular Weight 397.47
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms YN968D1
SMILES O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.