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Apatinib
SPC-00207
CAS No. 811803-05-1
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5 mg | Online Inquiry |
25 mg | Online Inquiry |
100 mg | Online Inquiry |
Bulk Size | Online Inquiry |
VEGFR inhibitor ; c-RET inhibitor ; c-Kit inhibitor ; Src inhibitor ; Autophagy activator ; Apoptosis related activator
Description |
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Apatinib is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret, c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis. |
Product Details | |
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CAS No. | CAS No. 811803-05-1 |
Description | Apatinib is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret, c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis. |
Formula | C24H23N5O |
Molecular Weight | 397.47 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | YN968D1 |
SMILES | O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3 |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.