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Annexin V Antibody
SPA-00529
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Annexin V |
| Gene Abbr. | ANXA5 |
| Gene ID | 308 |
| Full Name | annexin A5 |
| Alias | ANX5, ENX2, HEL-S-7, PP4, RPRGL3 |
| Introduction | During apoptosis, phosphatidylserine (PS) is trans located from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 38701 |
| Isotype | IgG2A |
| Immunogen | E. coli-derived recombinant human Annexin V. Met1-Asp320. P08758. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (0.25 µg/mL); Immunohistochemistry (5-25 µg/mL) |
| Reactivity | Human |
| Validation | Knockout Validated. |
| Specificity | Detects human Annexin V in direct ELISAs. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.