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Annexin V Antibody
SPA-00528
| Size | Price |
| 0.1 mL | Online Inquiry |
| 25 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Annexin V |
| Gene Abbr. | ANXA5 |
| Gene ID | 308 |
| Full Name | annexin A5 |
| Alias | ANX5, ENX2, HEL-S-7, PP4, RPRGL3 |
| Introduction | During apoptosis, phosphatidylserine (PS) is trans located from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | VAA-33 |
| Isotype | IgG2A |
| Immunogen | Recombinant Annexin V. |
| Usage | |
|---|---|
| Application | ELISA, FC |
| Dilutions | ELISA (1:100-1:2000); Flow Cytometry (1:10-1:1000) |
| Reactivity | Human |
| Specificity | Specifically recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.