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Aminoacylase/ACY1 Antibody
SPA-00441
| Size | Price |
| 100 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Aminoacylase/ACY1 |
| Gene Abbr. | ACY1 |
| Gene ID | 95 |
| Full Name | aminoacylase 1 |
| Alias | ACY-1, ACY1D, HEL-S-5 |
| Introduction | Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 475626 |
| Isotype | IgG2B |
| Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Aminoacylase/ACY1. Thr2-Ser408. Accession # Q03154. |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (1 µg/mL); Immunoprecipitation (25 µg/mL) |
| Reactivity | Human |
| Specificity | Detects recombinant human Aminoacylase/ACY1 in direct ELISAs and Western Blots. In Western Blots, approximately 50% cross-reactivity with recombinant mouse ACY1 is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.