Aminoacylase/ACY1 Antibody - CD BioSciences

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Aminoacylase/ACY1 Antibody

Aminoacylase/ACY1 Antibody

SPA-00440

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100 µL Online Inquiry
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Target Information
Target Name Aminoacylase/ACY1
Gene Abbr. ACY1
Gene ID 95
Full Name aminoacylase 1
Alias ACY-1, ACY1D, HEL-S-5
Introduction Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Aminoacylase/ACY1. Thr2-Ser408. Accession # Q03154.
Usage
Application WB, IP
Dilutions Western Blot (0.1 µg/mL); Immunoprecipitation (25 µg/mL)
Reactivity Human
Specificity Detects human and mouse Aminoacylase/ACY1 in direct ELISAs and Western Blots.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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