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ALDH18A1 (-) Cell Line
SPL-00202
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| ALDH18A1 (-) |
| Target Information | |
|---|---|
| Target Name | ALDH18A1 |
| Gene Abbr. | ALDH18A1 |
| Gene ID | 5832 |
| Full Name | aldehyde dehydrogenase 18 family member A1 |
| Alias | ADCL3, ARCL3A, GSAS, P5CS, PYCS |
| Species | Human |
| Introduction | This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | ALDH18A1 (-) |
| Description | ALDH18A1 (-) |
| Parental Cell Line | C631 |
| Handling Specifications | |
|---|---|
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.